Real Madrid and Manchester City once again find themselves inseparable in Europe’s top competition, with another high-stakes showdown awaiting in Gameweek 6 on Wednesday night. The two giants, familiar foes on the continental stage, now prepare for yet another chapter in their growing rivalry.
Check out The Betting Professionals’s analysis for Real Madrid vs Manchester City Champions League 2025-26 match on Matchday 6 with best football betting sites and predictions.
Real Madrid vs Manchester City Champions League 2025-26 Match Details
Date: Wednesday, 10th December 2025/Thursday, 11th December 2025
Time: 08:00 PM (GMT) / 01:30 AM (IST)
Venue: Santiago Bernabéu, Madrid, Spain
Real Madrid vs Manchester City Match Preview Champions League 2025-26
Real Madrid enter Wednesday’s showdown under real strain. Four points behind Barcelona, with just two wins from seven and a chaotic home loss to Celta Vigo marked by injuries, missed chances and three red cards, Los Blancos look unsettled. Alonso’s electric start has faded, and questions over his future have grown, even as Real maintain strong Champions League form: 12 points from 15, a dramatic 4-3 win over Olympiacos via a Mbappé masterclass, and a perfect UCL home record this season.
Manchester City also arrive seeking redemption. A heavily rotated side suffered their first Champions League defeat of the campaign against Leverkusen, leaving Pep Guardiola to admit he over-rotated as City slipped outside the automatic last-16 places on goal difference. Still, three straight Premier League wins have steadied them.
City aim to halt a two-match losing streak against Real, but history is not on their side—just one win in seven Bernabeu visits, dating back to 2020.
Real Madrid vs Manchester City Team News - Champions League 2025-26
Real Madrid Team News
Real Madrid’s injury crisis remains severe, though their two La Liga red-card offenders are available for Wednesday. Alonso must decide whether to start Fran García or Álvaro Carreras, but his defensive options are scarce. Huijsen, Alaba, Militão, Mendy, Alexander-Arnold and Carvajal are all out, likely forcing Raúl Asencio to play right-back and pushing Valverde back into midfield.
Their diamond shape faltered without Alexander-Arnold at the weekend, so a tactical tweak is possible against Guardiola’s men.
The biggest worry is Kylian Mbappé, who suffered a knee injury versus Celta Vigo and is doubtful. Eduardo Camavinga has also picked up another setback.
Real Madrid Predicted Lineup
Courtois; Valverde, Asencio, Rudiger, Carreras; Tchouameni, Ceballos; Guler, Bellingham, Vinicius Jr; Garcia
Manchester City Team News
Man City’s injury situation is lighter than Madrid’s, but Guardiola is still without key players. Rodri remained out and was ruled “a few weeks away” from returning at the start of December. His natural understudy, Mateo Kovačić, faces an even longer absence due to an ankle injury that may keep him sidelined until the “final part of the season.” John Stones also joined the injury list last week.
Manchester City Predicted Lineup
Donnarumma; Nunes, Dias, Gvardiol, O'Reilly; Gonzalez; Cherki, Reijnders, Foden, Doku; Haaland
Real Madrid vs Manchester City Betting Odds - Champions League 2025-26 Match
In the table below, check out the latest betting odds for the champions league 2025-26 match between Real Madrid vs Manchester City, set to take place at Santiago Bernabéu, Madrid.
Match Result | Odds on 1xBet |
Real Madrid will win the match | 2.93 |
Manchester City will win the match | 2.35 |
Match will be drawn | 3.98 |
In the 1X2 market on 1xBet, Manchester City are priced as favourites at 2.35, while Real Madrid follow at 2.93. The draw is listed at 3.98.
Real Madrid vs Manchester City - Recommended Bets by TBP
Bet 1: Both Teams to score - Yes @ 1.4 at 1xBet
Bet 2: Total Goals over 3.5 - @ 2.22 at 1xBet
Real Madrid vs Manchester City Match Prediction
Given the current trajectories of both teams, Manchester City understandably enter as favourites. Guardiola continues to temper expectations, while Alonso faces mounting pressure amid talk of his job security. Yet the matchup is far from straightforward.
City’s defensive vulnerabilities out of possession remain a concern—Fulham’s sudden goal surge at Craven Cottage was a clear warning sign. Even without Mbappé, Real Madrid still possess enough attacking quality to exploit those gaps, with star power spread across their frontline.
A high-tempo, end-to-end contest feels likely, and a share of the spoils could be on the cards at the Bernabéu.
Prediction: Real Madrid 2–2 Manchester City
Find out here the 1000 Rs signup bonus sites
Need quick and seamless transactions for live betting? Check out our list on Top UPI Betting Sites —perfect for instant deposits and easy withdrawals.
