The Premier League’s first Manchester derby of the season takes place this Sunday, with Manchester City welcoming local rivals Manchester United.
Check out The Betting Professionals analysis for Manchester City vs Manchester United Premier League 2025-26 match with best football betting sites and predictions:
Manchester City vs Manchester United Premier League 2025-26 Match Details
Date: Sunday, 14th September 2025
Time: 04:30 PM (BST) / 09:00 AM (IST)
Venue: Etihad Stadium, Manchester
Manchester City vs Manchester United Match Preview Premier League 2025-26
Manchester City began the season with a dominant 4-0 victory over Wolves but have since suffered back-to-back defeats against Tottenham and Brighton, conceding four goals while scoring just once.
Manchester United, meanwhile, have managed only one win in their first four competitive fixtures. After a Gameweek 1 loss to Arsenal, the Red Devils were held to a draw by Fulham, suffered a shocking EFL Cup defeat to League Two side Grimsby Town, and secured a late win over Burnley.
Manchester City vs Manchester United Team News - Premier League 2025-26
Manchester City Team News
Omar Marmoush will miss the Manchester derby with an injury from international duty, joining Kovačić, Cherki, and Aït-Nouri on the sidelines. John Stones is doubtful after withdrawing from England duty, while Foden, Gvardiol, Khusanov, Savinho, Lewis, and O’Reilly are fit. Guardiola is undecided if new signing Donnarumma will start over James Trafford.
Manchester City Predicted Lineup
Donnarumma; Nunes, Dias, Aké, Gvardiol; Rodri; Bobb, Silva, Reijnders, Doku; Haaland
Manchester United Team News
Amorim has confirmed that Matheus Cunha, Mason Mount, and Diogo Dalot will miss the derby, joining long-term absentee Lisandro Martínez on the sidelines and leaving the coach with several selection challenges.
André Onana’s exit ensures Altay Bayındır will start in goal, with Amorim backing the Türkiye international despite the arrival of Senne Lammens. Bruno Fernandes is expected to take a more advanced role to cover Cunha’s creativity, Benjamin Šeško could make his Premier League debut, and Kobbie Mainoo and Noussair Mazraoui may also feature.
Manchester United Predicted Lineup
Bayındır; Yoro, De Ligt, Shaw; Mazraoui, Casemiro, Mainoo, Dorgu; Mbeumo, Fernandes; Šeško
Manchester City vs Manchester United Betting Odds - Premier League 2025-26 Match
In the table below, check out the latest betting odds for the premier league 2025-26 match between Manchester City vs Manchester United, set to take place at Etihad Stadium, Manchester.
Match Result | Odds on 1xBet |
Manchester City will win the match | 1.80 |
Manchester United will win the match | 4.43 |
Match will be drawn | 4.25 |
In the 1X2 market on 1xBet, Manchester City are favorites at 1.80, Manchester United are priced at 4.43, and a draw is available at 4.25.
Manchester City vs Manchester United - Recommended Bets by TBP
Bet 1: Both Teams to score - Yes @ 1.52 at 1xBet
Bet 2: Total Goals over 3.5 - @ 2.41 at 1xBet
Manchester City vs Manchester United Match Prediction
Manchester City have been favourites in most recent Manchester derbies, but victories are not guaranteed—they’ve lost two of their last four encounters, including a dramatic late defeat at the Etihad last season. United have shown promising signs under Amorim despite mixed results and could test a City defence that has looked vulnerable. With both teams’ inconsistent starts to the season, a draw seems plausible.
Prediction: Manchester City 2–2 Manchester United.
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