A possibly distracted Liverpool face a challenging road back to winning form in the Champions League, with a tough San Siro test against Inter awaiting them on Tuesday night.
Check out The Betting Professionals’s analysis for Inter vs Liverpool Champions League 2025-26 match on Matchday 6 with best football betting sites and predictions.
Inter vs Liverpool Champions League 2025-26 Match Details
Date: Tuesday, 09th December 2025/Wednesday, 10th December 2025
Time: 08:00 PM (GMT) / 01:30 AM (IST)
Venue: San Siro, Milan
Inter vs Liverpool Match Preview Champions League 2025-26
Liverpool’s Champions League journey has swung wildly this season — from the high of beating Real Madrid to the low of a humiliating 4-1 loss to PSV, a result that matched a 96-year-old club record. That defeat marked their third home loss by three or more goals in 2025-26, leaving them outside the top eight and piling pressure on Arne Slot’s squad.
A three-game unbeaten run has done little to ease concerns. A routine win at West Ham was followed by flat draws against Sunderland and Leeds, the latter ending in a 96th-minute equaliser and a post-match bombshell from Mohamed Salah, who accused the club of scapegoating him and revealed a broken relationship with Slot. The board’s continued support of their manager only fuels speculation that Salah’s Liverpool chapter may be closing.
Whether he features in Milan or not, Liverpool are aiming for a fourth straight European win over Italian opponents — but recent form suggests a tough night ahead.
Inter also suffered a setback in their last Champions League outing, losing 2-1 at Atletico Madrid via a stoppage-time strike, though that defeat lacks the alarm of Liverpool’s PSV collapse. Before that, Cristian Chivu’s side were perfect in Europe, cruising past manageable opposition and climbing to fourth in the 36-team table, level with Bayern, Real Madrid and PSG.
Domestically, Inter are flying. Three straight wins in Serie A and the Coppa Italia — by an 11-1 aggregate — underline their momentum, capped by a dominant 4-0 victory over Como.
Liverpool did win 2-0 at San Siro in 2021-22, but Inter have since turned their home into a fortress, winning 10 of their last 11 Champions League group/league-phase matches. With Slot’s champions struggling, the Nerazzurri justifiably enter as strong favourites.
Inter vs Liverpool Team News - Champions League 2025-26
Inter Team News
Inter were superb in their weekend win over Como, and Chivu may be tempted to stick with the same XI for Liverpool’s visit. However, with this being their fourth match in 10 days, rolling out an unchanged lineup would be a gamble.
Should rotation come into play, Yann Bisseck could slot into the backline, summer signing Petar Sučić may get a midfield start, and Ange-Yoan Bonny could join Lautaro Martínez in attack. The Inter captain — who found the net at Anfield in their last meeting — heads into this clash in outstanding form.
Inter Predicted Lineup
Sommer; Acerbi, Bisseck, Bastoni; Augusto, Zielinski, Barella, Calhanoglu, Dimarco; Thuram, Martinez
Liverpool Team News
Salah’s explosive post-match remarks at Elland Road have shifted much of the pre-game spotlight onto the Egyptian, who has been omitted from Liverpool’s squad entirely for Tuesday’s clash.
He has featured sparingly in recent weeks — unused in two of the last three Premier League games and playing only 45 minutes against Sunderland — increasing scrutiny over his situation.
In his absence, Arne Slot is expected to keep Dominik Szoboszlai on the right, supported by Conor Bradley at fullback, with the Northern Irishman making his return from injury at the weekend.
Bradley’s comeback leaves Jeremie Frimpong, Giovanni Leoni and Stefan Bajcetic as Liverpool’s only unavailable players.
Liverpool Predicted Lineup
Alisson; Bradley, Gomez, Van Dijk, Robertson; Gravenberch, Jones; Szoboszlai, Wirtz, Ekitike; Isak
Inter vs Liverpool Betting Odds - Champions League 2025-26 Match
In the table below, check out the latest betting odds for the champions league 2025-26 match between Inter Milan vs Liverpool, set to take place at San Siro, Milan.
Match Result | Odds on 1xBet |
Inter will win the match | 2.03 |
Liverpool will win the match | 3.81 |
Match will be drawn | 3.82 |
In the 1X2 market on 1xBet, Inter enter as favourites at 2.03, Liverpool sit at 3.81, and the draw is listed at 3.82.
Inter vs Liverpool - Recommended Bets by TBP
Bet 1: Both Teams to score - Yes @ 1.56 at 1xBet
Bet 2: Total Goals over 2.5 - @ 1.71 at 1xBet
Inter vs Liverpool Match Prediction
Liverpool and Slot are showing little sign of stability, and their supporters will travel to San Siro with hope more than conviction.
Those concerns are likely to be realised, as a cohesive, free-scoring, Martínez-driven Inter side should have too much for the visitors, deepening the questions surrounding Slot’s future.
Prediction: Inter Milan 3-1 Liverpool
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