Taking a brief break from their ongoing Premier League relegation struggle, Tottenham Hotspur shift their focus to European action as they travel to the Wanda Metropolitano to face Atletico Madrid in the first leg of their Champions League Round of 16 clash on Tuesday.
Despite their disappointing domestic campaign, the Europa League holders impressed during the league phase of the competition, finishing fourth to secure a direct place in the knockout rounds. Meanwhile, Diego Simeone’s Atletico Madrid booked their spot in the last 16 after successfully overcoming Club Brugge in the playoff round.
In this article, we bring the Atletico Madrid vs Tottenham champions league 2025-26 round of 16 match preview, analysis and prediction along with the best football betting sites.
Atletico Madrid vs Tottenham Match Details
Competition: UEFA Champions League 2025-26
Matchday: Round of 16 Leg 1
Date: Tuesday, 10th March 2026 / Wednesday, 11th March 2026
Kick-off: 8:00 PM GMT / 1:30 AM IST
Venue: Riyadh Air Metropolitano
Atletico Madrid vs Tottenham Match Preview
European competition has provided a rare escape for Tottenham Hotspur amid their disastrous domestic campaign. While Spurs continue to struggle in the Premier League, they have been far more convincing in Europe this season.
The Europa League holders impressed during the league phase, recording five victories, including 2-0 wins over Borussia Dortmund and Eintracht Frankfurt. Those results helped them finish ahead of several European giants such as Paris Saint-Germain, Barcelona, Manchester City, Real Madrid and Chelsea in the expanded 36-team standings.
However, Tottenham arrive in Madrid in dreadful domestic form. Their 3-1 defeat to Crystal Palace extended their winless Premier League run to 11 matches, leaving them just one point above the relegation zone. The loss also marked their fifth consecutive defeat across all competitions under Igor Tudor.
Meanwhile, Atletico Madrid secured their place in the last 16 after overcoming Club Brugge in a dramatic playoff tie. A thrilling first-leg draw was followed by a dominant 4-1 victory at home, inspired by a hat-trick from Alexander Sorloth.
Despite their reputation for defensive solidity under Diego Simeone, Atletico conceded 15 goals during the league phase—the worst defensive record among the top-16 teams.
Still, the Spanish side head into this clash with strong home form, winning four straight matches at the Wanda Metropolitano while scoring at least three goals in each victory.
With Tottenham’s domestic struggles continuing, this first-leg clash promises to be a major test for the visiting side.
Atletico Madrid vs Tottenham Team News
Tottenham Hotspur will have key defenders available despite their recent league setback. Micky van de Ven was sent off against Crystal Palace, but his suspension applies only to domestic matches, meaning he is eligible for Tuesday’s clash. Cristian Romero also returns after serving his Premier League ban.
Spurs enjoyed a weekend break following their early exit from the FA Cup. Igor Tudor could welcome back Djed Spence from a calf injury, while Destiny Udogie is close to returning from a thigh issue.
However, injuries continue to trouble Tottenham. Wilson Odobert and James Maddison remain out with ACL injuries, while Dejan Kulusevski (knee), Ben Davies (ankle), Lucas Bergvall (ankle), Mohammed Kudus (thigh) and Rodrigo Bentancur (thigh) are also sidelined. Radu Dragusin remains a doubt after missing the Palace defeat with a knock.
For Atletico Madrid, January signing Rodrigo Mendoza picked up an ankle injury against Real Sociedad and could be out for several weeks. Midfielder Pablo Barrios has returned to training after a hamstring problem and may be available.
Antoine Griezmann impressed off the bench in Atletico’s last match, while Nico Gonzalez scored twice, putting both players in contention for a starting spot.
Atletico Madrid vs Tottenham Predicted Lineups
Atletico Madrid Predicted Lineup
Oblak; Llorente, Le Normand, Hancko, Ruggeri; Simeone, Koke, Barrios, Gonzalez; Sorloth, Alvarez
Tottenham Predicted Lineup
Vicario; Danso, Romero, Van de Ven; Porro, Palhinha, Sarr, Gray; Simons; Richarlison, Solanke
Atletico Madrid vs Tottenham Betting Odds (1X2 – 1xBet)
Atletico Madrid win: 1.76
Draw: 3.87
Tottenham win: 5.22
Atletico Madrid are strong favourites for winning this match against Tottenham.
Atletico Madrid vs Tottenham Recommended Bets (1xBet)
Both Teams to Score – No @ 1.89
Under 2.5 Total Goals @ 1.96
Atletico Madrid vs Tottenham Match Prediction
With Cristian Romero and Micky van de Ven reunited in defence, Tottenham Hotspur should look more solid at the back. However, Spurs still lack attacking creativity and a clear identity under Igor Tudor and an in-form Atletico Madrid side, strong at home, could take a major step toward the quarter-finals.
Final Prediction: Atletico Madrid 2 - 0 Tottenham
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